Alzheimer's disease (AD) is the most common cause of dementia, characterized by memory loss and cognitive impairments that interfere with daily life.
A growing body of evidence suggests that impaired brain energy metabolism and mitochondrial dysfunction contribute to cognitive decline in AD.
The phase 3 clinical trial aims to improve mitochondrial dysfunction by treating patients with the proprietary Combined Metabolic Activator (CMA2) drug.
The multicentre trial is taking place across nine clinical centres in Turkey, targeting patients with mild, moderate, and severe Alzheimer's symptoms.
Stockholm, Sweden - November 4, 2025- ScandiBio Therapeutics AB today announced the initiation of a multicentre, phase 3 human clinical trial evaluating the efficacy and safety of their pharmaceutical, Combined Metabolic Activator (CMA), in patients with Alzheimer's disease (AD).
Author's summary: ScandiBio starts phase 3 trial for Alzheimer's.