Melatonin's Potential Harm to the Heart
Researchers have discovered a surprising connection between long-term melatonin use and heart failure in patients with chronic insomnia.
Marketed as a natural sleep aid, melatonin has become a nightly routine for millions. However, new research presented at the American Heart Association's Scientific Sessions 2025 suggests that the supplement may have unintended consequences on the heart.
- Long-term melatonin use (for a year or more) was linked to a nearly doubled risk of developing heart failure.
- It more than tripled the risk of hospitalization for heart failure.
- It nearly doubled the risk of death over five years.
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This finding is based on a review of over 130,000 adults with insomnia.
Author's summary: Melatonin may harm the heart in insomnia patients.
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